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ADC Landscape

Pfizer (Seagen)

Nectin-4 · Urothelial / bladder cancer

ApprovedAntibody–Drug Conjugates
Target
Nectin-4
Payload
MMAE
Payload class
Auristatin
Linker
Cleavable val-cit
Indication
Urothelial / bladder cancer
Phase
Approved
Partner
Astellas

Overview

With pembrolizumab, became 1st-line standard in advanced bladder cancer — a landmark ADC+IO combination that beat chemo on overall survival.

Technology

Pfizer (Seagen) works in Antibody–Drug Conjugates — A guided missile: an antibody that flies a chemo warhead straight to the tumor.

Read the Antibody–Drug Conjugates brief →

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Company website / source ↗ Open the interactive map →

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Curated biotech intelligence, compiled for orientation — not investment advice. Company stages, deals and figures move fast; verify against ClinicalTrials.gov, company filings and primary sources before acting.