ADC Landscape
Pfizer (Seagen)
Tissue Factor · Cervical cancer
ApprovedAntibody–Drug Conjugates
Target
Tissue Factor
Payload
MMAE
Payload class
Auristatin
Linker
Cleavable val-cit
Indication
Cervical cancer
Phase
Approved
Partner
Genmab
Overview
First and only approved Tissue Factor ADC. Genmab antibody + Seagen conjugation — opened a novel target class.
Technology
Pfizer (Seagen) works in Antibody–Drug Conjugates — A guided missile: an antibody that flies a chemo warhead straight to the tumor.
Read the Antibody–Drug Conjugates brief →Related companies
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