ADC Landscape
Genmab (ProfoundBio)
FRα · Ovarian, endometrial cancer
Phase 3Antibody–Drug Conjugates
Target
FRα
Payload
Exatecan
Payload class
Topo-I inhibitor
Linker
Cleavable hydrophilic
Indication
Ovarian, endometrial cancer
Phase
Phase 3
Partner
— (Genmab acq. ProfoundBio $1.8B)
Overview
Next-gen FRα ADC with an exatecan payload and a homogeneous DAR-8 design — engineered to beat Elahere on therapeutic window. Anchored Genmab's ProfoundBio buy.
Technology
Genmab (ProfoundBio) works in Antibody–Drug Conjugates — A guided missile: an antibody that flies a chemo warhead straight to the tumor.
Read the Antibody–Drug Conjugates brief →Related companies
Daiichi Sankyo
HER2
Gilead
TROP2
AstraZeneca / Daiichi
TROP2
Pfizer (Seagen)
CD30
Pfizer (Seagen)
Nectin-4
Pfizer (Seagen)
Tissue Factor
Company website / source ↗ Open the interactive map →
◢ Boom-cycle briefing
Get ahead of the next biotech boom.
New companies, stage changes, deal alerts and fresh tech briefs — one sharp email when the map moves.
Curated biotech intelligence, compiled for orientation — not investment advice. Company stages, deals and figures move fast; verify against ClinicalTrials.gov, company filings and primary sources before acting.