ADC Landscape
Roche
CD79b · Diffuse large B-cell lymphoma
ApprovedAntibody–Drug Conjugates
Target
CD79b
Payload
MMAE
Payload class
Auristatin
Linker
Cleavable val-cit
Indication
Diffuse large B-cell lymphoma
Phase
Approved
Partner
— (Seagen tech)
Overview
Moved into 1st-line DLBCL (POLARIX), a major frontline win for an ADC in lymphoma.
Technology
Roche works in Antibody–Drug Conjugates — A guided missile: an antibody that flies a chemo warhead straight to the tumor.
Read the Antibody–Drug Conjugates brief →Related companies
Daiichi Sankyo
HER2
Gilead
TROP2
AstraZeneca / Daiichi
TROP2
Pfizer (Seagen)
CD30
Pfizer (Seagen)
Nectin-4
Pfizer (Seagen)
Tissue Factor
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